Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516454 | 0.99 | TSHR (0.39) | TSHRALDH1A1TDP1CYP2D6S1PR1 | |
| SCHEMBL13701401 | 0.88 | TSHR (0.39) | TSHRALDH1A1TDP1CYP2D6S1PR1 | |
| SCHEMBL13701396 | 0.88 | TSHR (0.39) | TSHRALDH1A1TDP1CYP2D6S1PR1 | |
| SCHEMBL29829574 | 0.86 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1S1PR1SGPL1 | |
| SCHEMBL4257286 | 0.86 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1S1PR1SGPL1 | |
| SCHEMBL4263589 | 0.86 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1S1PR1SGPL1 | |
| SCHEMBL4258515 | 0.86 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1S1PR1SGPL1 | |
| SCHEMBL4269346 | 0.86 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1S1PR1SGPL1 | |
| SCHEMBL31516452 | 0.86 | ALDH1A1 (0.34) | ALDH1A1CYP2D6S1PR1SGPL1CYP2C19 | |
| SCHEMBL13701408 | 0.86 | TSHR (0.40) | TSHRALDH1A1TDP1CYP2D6S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094865-B2 | Thiophenes and polymers derived therefrom | AGFA GEVAERT (BE) | 2006-08-22 | — | — | US | disclosed |
| EP-1390422-B1 | THIOPHENES AND POLYMERS DERIVED THEREFROM | AGFA GEVAERT (BE) | 2004-11-03 | — | — | EP | disclosed |
| US-20030055130-A1 | New thiophenes and polymers derived therefrom | AGFA-GEVAERT (BE) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055130-A1 | New thiophenes and polymers derived therefrom | NOTUM, WEE1, THEM6 | TSHR 2260/4885ALDH1A1 136/4885TDP1 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.