Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701423 | 0.86 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL4276680 | 0.85 | HPGD (0.53) | S1PR1KDM4EHSD17B10RAB9AALDH1A1 | |
| SCHEMBL4273678 | 0.85 | MAPT (0.48) | S1PR1KDM4EHSD17B10RAB9AALDH1A1 | |
| SCHEMBL4274950 | 0.84 | HSD17B10 (0.49) | S1PR1KDM4EHSD17B10RAB9AALDH1A1 | |
| SCHEMBL4273688 | 0.83 | S1PR1 (0.51) | S1PR1KDM4EHSD17B10RAB9ALMNA | |
| SCHEMBL13701420 | 0.83 | DHODH (0.43) | KDM4EHSD17B10ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4283029 | 0.82 | MAPT (0.46) | S1PR1KDM4EHSD17B10RAB9AALDH1A1 | |
| SCHEMBL4278834 | 0.82 | S1PR1 (0.50) | S1PR1KDM4EHSD17B10RAB9AALDH1A1 | |
| SCHEMBL15450565 | 0.82 | HPGD (0.40) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL13701421 | 0.81 | PDE4B (0.46) | KDM4EALDH1A1HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637559-B2 | Oxazole compound and pharmaceutical composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-01-28 | — | — | US | disclosed |
| US-20090221586-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221586-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | PDE3B, PDE4A, PDE3A | S1PR1 964/4885KDM4E 1260/4885HSD17B10 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.