SCHEMBL4283029

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273678	0.89	MAPT (0.48)	MAPTHPGDKDM4EHSD17B10TP53
	SCHEMBL4280727	0.83	KDM4E (0.43)	MAPTHPGDKDM4EHSD17B10NPSR1
	SCHEMBL4276680	0.83	HPGD (0.53)	MAPTHPGDKDM4EHSD17B10MAPK1
	SCHEMBL13701419	0.82	S1PR1 (0.45)	MAPTHPGDKDM4EHSD17B10TP53
	SCHEMBL4273688	0.82	S1PR1 (0.51)	MAPTKDM4EHSD17B10TP53MEN1
	SCHEMBL4271699	0.79	MAPT (0.51)	MAPTHPGDKDM4EHSD17B10TP53
	SCHEMBL4275015	0.79	HPGD (0.50)	MAPTHPGDKDM4EHSD17B10NPSR1
	SCHEMBL4279491	0.79	KCNK3 (0.47)	MAPTHPGDKDM4EHSD17B10TP53
	SCHEMBL4278342	0.77	HPGD (0.50)	MAPTHPGDKDM4EHSD17B10NPSR1
	SCHEMBL4274950	0.77	HSD17B10 (0.49)	MAPTHPGDKDM4EHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.