Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701680 | 0.85 | KCNQ3 (0.48) | RIPK1DYRK1ACDK8LMNAABL1 | |
| SCHEMBL13701679 | 0.85 | NPC1 (0.47) | RIPK1DYRK1ACDK8LMNANPC1 | |
| SCHEMBL13611934 | 0.83 | KMO (0.61) | RIPK1DYRK1AKMOEGLN1P4HTM | |
| SCHEMBL13701640 | 0.83 | MEN1 (0.60) | — | |
| SCHEMBL13701676 | 0.81 | GAA (0.44) | RIPK1DYRK1ACDK8LMNA | |
| SCHEMBL14507838 | 0.81 | ERN1 (0.56) | RIPK1DYRK1AABL1BCR | |
| SCHEMBL13702257 | 0.81 | CDK8 (0.62) | RIPK1CDK8GRM5ALDH1A1CYP2C19 | |
| SCHEMBL13701695 | 0.79 | HDAC8 (0.64) | GRM5LMNAKMO | |
| SCHEMBL5562440 | 0.79 | CDK8 (0.60) | CDK8ALDH1A1ABL1BCR | |
| SCHEMBL13701643 | 0.79 | KAT6A (0.54) | DYRK1ACYP2C19LMNAABL1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | RIPK1 2878/4885DYRK1A 4221/4885CDK8 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.