Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611934 | 0.89 | KMO (0.61) | DYRK1AMKNK1MKNK2EGLN1P4HTM | |
| SCHEMBL13701678 | 0.88 | KAT6A (0.56) | MKNK1MKNK2KAT6A | |
| SCHEMBL12251075 | 0.85 | MKNK1 (0.70) | DYRK1AMKNK1MKNK2EGLN1P4HTM | |
| SCHEMBL2732281 | 0.83 | HDAC1 (0.62) | CYP11B1CYP11B2HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL31268672 | 0.83 | HDAC1 (0.62) | CYP11B1CYP11B2HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL13701655 | 0.82 | ABL1 (0.50) | ABL1MKNK1MKNK2KAT6ACYP1A2 | |
| SCHEMBL18496661 | 0.82 | DYRK1A (0.52) | DYRK1AMKNK1MKNK2EGLN1P4HTM | |
| SCHEMBL13701652 | 0.81 | EGFR (0.54) | DYRK1AMKNK1MKNK2EGLN1P4HTM | |
| SCHEMBL13702258 | 0.80 | GAA (0.52) | ABL1OPRM1KCNH2MKNK1MKNK2 | |
| SCHEMBL13188758 | 0.79 | HDAC1 (0.63) | ABL1OPRM1KCNH2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | ABL1 4720/4885OPRM1 3613/4885KCNH2 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.