SCHEMBL13703263

SCHEMBL13703263

Cc1cc(C)c(B(c2ccc(-c3ccc(C(c4ccc(-c5ccccc5)cc4)(c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccccc5)cc4)cc3)cc2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
PSMB5 P28074 2/20 0.38
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MGLL Q99685 1/20 0.35
KIF11 P52732 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
MAPK8 P45983 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
ESR2 Q92731 3/20 0.32
ESR1 P03372 2/20 0.32
CYP2C9 P11712 1/20 0.32
MAPT P10636 2/20 0.32
GAA P10253 1/20 0.32
ALOX12 P18054 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13703255 0.92 FFAR4 (0.41) ALDH1A1PSMB5KIF11FFAR4ESR2
SCHEMBL13703261 0.92 FFAR4 (0.41) ALDH1A1PSMB5KIF11FFAR4ESR2
SCHEMBL85808 0.83 RAPGEF4 (0.37) SMN1; SMN2LMNAALDH1A1PSMB5CA2
SCHEMBL7458255 0.83 RAPGEF4 (0.37) SMN1; SMN2LMNAALDH1A1PSMB5CA2
SCHEMBL10100958 0.82 MEN1 (0.42) SMN1; SMN2LMNAALDH1A1PSMB5CA2
SCHEMBL18742863 0.80 THRA (0.33) PSMB5FFAR4
SCHEMBL10100950 0.79 ESR1 (0.36) PSMB5FFAR4RXRARXRBESR1
SCHEMBL7458913 0.79 FFAR4 (0.43) SMN1; SMN2LMNAPSMB5FFAR4MAPT
SCHEMBL7908988 0.79 FFAR4 (0.46) SMN1; SMN2LMNAPSMB5FFAR4MAPT
SCHEMBL7461562 0.78 PSMB5 (0.42) SMN1; SMN2LMNAALDH1A1PSMB5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7588839-B2 Electroluminescent device EASTMAN KODAK COMPANY (US) 2009-09-15 US disclosed
US-7588839-B2 Electroluminescent device EASTMAN KODAK COMPANY (US) 2009-09-15 US disclosed
US-20070087219-A1 Efficient OLEDs having an emissive layer having host material with a wide energy gap and comprising a disilyl compound, e.g., SiPh2(o-tolyl)2 diphenyldi(o-tolyl)silane or p-(SiPh3)2Ph p-bis(triphenylsilyl)benzene or a phosphine oxide or borane-containing silyl compound EASTMAN KODAK COMPANY 2007-04-19 US disclosed
US-20070087219-A1 Efficient OLEDs having an emissive layer having host material with a wide energy gap and comprising a disilyl compound, e.g., SiPh2(o-tolyl)2 diphenyldi(o-tolyl)silane or p-(SiPh3)2Ph p-bis(triphenylsilyl)benzene or a phosphine oxide or borane-containing silyl compound EASTMAN KODAK COMPANY 2007-04-19 US disclosed