Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | MC1R | Q01726 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | OXTR | P30559 | 5/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | NPR1 | P16066 | 1/20 | 0.40 |
| ▸ | NPR3 | P17342 | 1/20 | 0.40 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929553 | 0.92 | MC4R (0.46) | MDM2MC4RMC5RMC3RMC1R | |
| SCHEMBL13703200 | 0.83 | MC4R (0.52) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL13703448 | 0.82 | MC4R (0.53) | MDM2MC4RMC5RMC3RMC1R | |
| SCHEMBL13649555 | 0.81 | MC4R (0.56) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL13649564 | 0.80 | MC4R (0.55) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL13703202 | 0.79 | MC4R (0.52) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL11929552 | 0.78 | ITGB3 (0.57) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL13649552 | 0.77 | MDM2 (0.51) | MDM2ESR1OXTRAVPR1AAVPR1B | |
| SCHEMBL13656564 | 0.77 | MC4R (0.49) | MDM2MC4RMC5RMC3RMC1R | |
| SCHEMBL11929915 | 0.74 | MC4R (0.58) | MDM2MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090232741-A1 | Optical Imaging | GE HEALTHCARE AS (NO) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090232741-A1 | Optical Imaging | AGER, KDR, FLT4 | MDM2 4012/4885MC4R 244/4885MC5R 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.