Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 10/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664563 | 0.91 | GCK (0.46) | GCKCSNK2A2CSNK2A1RARARARB | |
| SCHEMBL14191883 | 0.90 | FFAR2 (0.41) | GCKFFAR2CSNK2A2CSNK2A1RARA | |
| SCHEMBL14546873 | 0.84 | FFAR2 (0.40) | GCKFFAR2CSNK2A2CSNK2A1RARA | |
| SCHEMBL14092862 | 0.82 | FFAR2 (0.37) | GCKFFAR2CSNK2A2CSNK2A1RARA | |
| SCHEMBL2664562 | 0.80 | GCK (0.46) | GCKFFAR2CSNK2A2CSNK2A1RARA | |
| SCHEMBL13678510 | 0.80 | GCK (0.40) | GCKFFAR2RARARARBRARG | |
| SCHEMBL2664723 | 0.78 | GCK (0.51) | GCKCSNK2A2CSNK2A1RARARARB | |
| SCHEMBL2666434 | 0.75 | GCK (0.44) | GCKCSNK2A2CSNK2A1RARARARB | |
| SCHEMBL14546724 | 0.75 | GCK (0.62) | GCKFFAR2CSNK2A2CSNK2A1RARA | |
| SCHEMBL2664568 | 0.73 | GCK (0.46) | GCKCSNK2A2CSNK2A1RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529530-B3 | Compounds affecting glucokinase | ASTRAZENECA AB (SE) | 2009-09-02 | — | — | EP | disclosed |