Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874915 | 0.83 | CCR1 (0.46) | CCR1CCR5CCR8 | |
| SCHEMBL28308505 | 0.81 | CCR1 (0.44) | CCR1CCR5CCR8 | |
| Water SCHEMBL28540792 | 0.81 | CCR1 (0.44) | CCR1CCR5CCR8 | |
| SCHEMBL27333834 | 0.81 | CCR1 (0.44) | CCR1CCR5CCR8 | |
| Ammonia Solution, Strong SCHEMBL28562820 | 0.81 | CCR1 (0.44) | CCR1CCR5CCR8 | |
| Iodide SCHEMBL28183168 | 0.81 | CCR1 (0.44) | CCR1CCR5CCR8 | |
| Ethylenediamine SCHEMBL6295958 | 0.77 | CCR1 (0.38) | CCR1CCR5CCR8 | |
| Formic Acid SCHEMBL28325338 | 0.71 | CCR1 (0.37) | CCR1CCR5CCR8 | |
| SCHEMBL3671331 | 0.69 | NOS3 (0.44) | CCR1CCR5CCR8 | |
| SCHEMBL14438199 | 0.64 | CCR1 (0.37) | CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5603820-A | ELECTRICALLY CONDUCTIVE SUBSTRATE HAVING ADHERENT UNIFORM ELECTROCHEMICALLY ACTIVE POLYMERIC COATING FORMED ON SURFACE WHICH INTERACTS WITH NITRIC OXIDE TO CHANGE REDOX POTENTIAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-02-18 | — | — | US | claimed |
| WO-1994002845-A1 | NITRIC OXIDE-SPECIFIC ELECTRODE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-02-03 | — | — | WO | claimed |
| US-9510780-B2 | Sensors for detecting substances in bodily fluids | SILVER JAMES H (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150230742-A1 | SENSORS FOR DETECTING SUBSTANCES IN BODILY FLUIDS | SILVER JAMES H (US) | 2015-08-20 | — | — | US | disclosed |
| US-9044182-B2 | Sensors for detecting substances in bodily fluids | SILVER JAMES H (US) | 2015-06-02 | — | — | US | disclosed |
| US-8609426-B2 | Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation | SILVER JAMES H (US) | 2013-12-17 | — | — | US | disclosed |
| US-20130202721-A1 | SENSORS FOR DETECTING SUBSTANCES IN BODILY FLUIDS | SILVER JAMES H (US) | 2013-08-08 | — | — | US | disclosed |
| US-20120135531-A1 | SENSORS FOR DETECTING SUBSTANCES INDICATIVE OF STROKE, ISCHEMIA, INFECTION OR INFLAMMATION | SILVER JAMES H (US) | 2012-05-31 | — | — | US | disclosed |
| US-8133698-B2 | Apparatus which measures concentration nitric oxide or one of its metabolic products; detector for monitoring glucose levels in body vessel; diagnosing cardiovascular disorders | SILVER JAMES H (US) | 2012-03-13 | — | — | US | disclosed |
| US-20120058012-A1 | SENSORS FOR DETECTING SUBSTANCES INDICATIVE OF STROKE, ISCHEMIA, INFECTION OR INFLAMMATION | N2ITIVE1 INNOVATIONS | 2012-03-08 | — | — | US | disclosed |
| US-8114350-B1 | Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation | N2ITIVE1 INNOVATIONS | 2012-02-14 | — | — | US | disclosed |
| US-7769420-B2 | Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction | SILVER JAMES H | 2010-08-03 | — | — | US | disclosed |
| US-20080176271-A1 | SENSORS FOR DETECTING SUBSTANCES INDICATIVE OF STROKE, ISCHEMIA, INFECTION OR INFLAMMATION | SILVER JAMES H | 2008-07-24 | — | — | US | disclosed |
| WO-2008089282-A2 | SENSORS FOR DETECTING SUBTANCES INDICATIVE OF STROKE, ISCHEMIA, INFECTION OR INFLAMMATION | SILVER JAMES H (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2007058872-A2 | DETECTING MARKERS OF STROKE, ISCHEMIA, OR MYOCARDIAL INFACTION | SILVER JAMES H (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20060129041-A1 | Guidewire with chemical sensing capabilities | ELLIS JEFFREY T | 2006-06-15 | — | — | US | disclosed |
| US-20060079740-A1 | Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction | SILVER JAMES H | 2006-04-13 | — | — | US | disclosed |
| US-7025734-B1 | Guidewire with chemical sensing capabilities | ADVANCED CARDIOVASCULAR SYSTMES, INC. (US) | 2006-04-11 | — | — | US | disclosed |
| US-5603820-A | ELECTRICALLY CONDUCTIVE SUBSTRATE HAVING ADHERENT UNIFORM ELECTROCHEMICALLY ACTIVE POLYMERIC COATING FORMED ON SURFACE WHICH INTERACTS WITH NITRIC OXIDE TO CHANGE REDOX POTENTIAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-02-18 | — | — | US | disclosed |
| WO-1994002845-A1 | NITRIC OXIDE-SPECIFIC ELECTRODE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-02-03 | — | — | WO | disclosed |