Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.43 |
| ▸ | ACLY | P53396 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705486 | 0.91 | KDM4E (0.47) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL13705498 | 0.81 | MAPT (0.46) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL13705629 | 0.81 | KDM4E (0.48) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL13705489 | 0.76 | KDM4E (0.53) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL13705499 | 0.75 | KMT2A (0.44) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL13705572 | 0.75 | KDM4E (0.50) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL13705497 | 0.74 | MAPT (0.48) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL24916802 | 0.73 | MAPT (0.52) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL12230785 | 0.71 | KDM4E (0.68) | MAPTKDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL13705494 | 0.70 | AKR1C3 (0.42) | MAPTKDM4ELMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |