Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705572 | 0.83 | KDM4E (0.50) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL24916802 | 0.81 | MAPT (0.52) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL13705486 | 0.80 | KDM4E (0.47) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL13705629 | 0.79 | KDM4E (0.48) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL13705487 | 0.76 | MAPT (0.46) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL12230785 | 0.75 | KDM4E (0.68) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL13705498 | 0.74 | MAPT (0.46) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL2261298 | 0.73 | KDM4E (0.60) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL7528635 | 0.73 | KDM4E (0.65) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL4459254 | 0.71 | KDM4E (0.59) | KDM4EMAPTHPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |