Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705486 | 0.78 | KDM4E (0.47) | ALDH1A1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL13705499 | 0.74 | KMT2A (0.44) | ALDH1A1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL13705490 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5106389 | 0.69 | KDM4E (0.53) | AKR1C3AKR1C2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17206259 | 0.68 | KDM4E (0.52) | AKR1C3AKR1C2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL99419 | 0.68 | ALDH1A1 (0.57) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL4961133 | 0.66 | PTPN1 (0.50) | PPARGALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL28201164 | 0.65 | ALDH1A1 (0.58) | ALDH1A1KMT2AL3MBTL1KDM4ENPSR1 | |
| SCHEMBL8471964 | 0.65 | ALDH1A1 (0.52) | ALDH1A1KMT2AL3MBTL1KDM4ENPSR1 | |
| SCHEMBL9312797 | 0.65 | ALDH1A1 (0.56) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |