SCHEMBL13705693

SCHEMBL13705693

O=Cc1cccc(-c2ccccc2OCc2ccccc2)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.60
CCNB2 O95067 1/20 0.52
CDK1 P06493 1/20 0.52
CDK4 P11802 1/20 0.52
CCNB1 P14635 1/20 0.52
CCND1 P24385 1/20 0.52
CCNB3 Q8WWL7 1/20 0.52
PTGER1 P34995 6/20 0.52
PTGER4 P35408 3/20 0.52
PTGER3 P43115 3/20 0.52
PTGER2 P43116 3/20 0.52
MCL1 Q07820 1/20 0.47
SRC P12931 1/20 0.47
TLR2 O60603 1/20 0.46
TLR1 Q15399 1/20 0.46
TLR6 Q9Y2C9 1/20 0.46
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46
LIPE Q05469 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13460838 0.89 ERN1 (0.53) ERN1CCNB2CDK1CDK4CCNB1
SCHEMBL13460601 0.89 ERN1 (0.50) ERN1CCNB2CDK1CDK4CCNB1
SCHEMBL13705697 0.89 MAOB (0.51) ERN1CCNB2CDK1CDK4CCNB1
SCHEMBL986050 0.88 CCNB2 (0.62) ERN1CCNB2CDK1CDK4CCNB1
SCHEMBL31683746 0.88 CCNB2 (0.62) ERN1CCNB2CDK1CDK4CCNB1
SCHEMBL13460592 0.84 RAB9A (0.50) ERN1PTGER1PTGER4PTGER3PTGER2
SCHEMBL12961849 0.84 ERN1 (0.47) ERN1PTGER1PTGER4PTGER3PTGER2
SCHEMBL12961822 0.81 ALDH1A1 (0.53) ERN1PTGER1MCL1TLR2TLR1
SCHEMBL13460843 0.81 ERN1 (0.56) ERN1CDK4CCND1TLR2TLR1
SCHEMBL433401 0.80 CCNB2 (0.72) ERN1CCNB2CDK1CDK4CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009116665-A1 PROCESS FOR PRODUCTION OF 2-HYDROXYARYL ALDEHYDE COMPOUND 日産化学工業株式会社 (JP) 2009-09-24 WO disclosed