Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306314 | 0.86 | KDM4E (0.67) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL27851276 | 0.84 | POLB (0.69) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL5430672 | 0.81 | KMT2A (0.64) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL17079635 | 0.81 | RAB9A (0.69) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL29609509 | 0.81 | RAB9A (0.69) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL1221514 | 0.81 | POLB (0.60) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL4299533 | 0.81 | KDM4E (0.60) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL22218698 | 0.80 | KMT2A (0.59) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL1222027 | 0.79 | KMT2A (0.57) | KMT2ASMN1; SMN2LMNAGAAITGB1 | |
| SCHEMBL29104584 | 0.76 | KDM4E (0.58) | KMT2ASMN1; SMN2NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221583-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221583-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | KMT2A 1389/4885SMN1; SMN2 4076/4885LMNA 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.