Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13897248 | 0.87 | MAPT (0.47) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL278904 | 0.79 | DPP4 (0.65) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL607254 | 0.77 | DPP4 (0.69) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL70783 | 0.77 | APP (0.67) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL12577701 | 0.76 | DPP4 (0.49) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL4218405 | 0.76 | KDM4E (0.47) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL7905308 | 0.73 | APP (0.68) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL10472980 | 0.73 | APP (0.73) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL5357392 | 0.72 | IMPDH2 (0.49) | DPP4KDM4EMAPTHPGDMEN1 | |
| SCHEMBL16140264 | 0.71 | DPP4 (0.62) | DPP4KDM4EMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589166-B2 | Thiophene-containing compound and polymer thereof | FUJI XEROX CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |
| US-7589166-B2 | Thiophene-containing compound and polymer thereof | FUJI XEROX CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |