Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706019 | 0.83 | — | — | |
| SCHEMBL12215859 | 0.79 | PIK3CD (0.41) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL13706011 | 0.74 | PIK3CD (0.32) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL13706005 | 0.73 | APP (0.34) | — | |
| SCHEMBL2169920 | 0.72 | MAPT (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL2172456 | 0.72 | PIK3CD (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL28057584 | 0.70 | HPGD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL13798607 | 0.70 | ESR2 (0.39) | ESR1ESR2 | |
| SCHEMBL3109171 | 0.68 | HSD17B1 (0.41) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1023559 | 0.68 | ESR1 (0.41) | PIK3CDABL1EGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589166-B2 | Thiophene-containing compound and polymer thereof | FUJI XEROX CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |