⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706018 | 0.83 | PIK3CD (0.37) | — | |
| SCHEMBL12215859 | 0.76 | PIK3CD (0.41) | — | |
| SCHEMBL5367283 | 0.76 | — | — | |
| SCHEMBL1466497 | 0.76 | — | — | |
| SCHEMBL15220268 | 0.74 | ERN1 (0.38) | — | |
| SCHEMBL4973329 | 0.73 | — | — | |
| SCHEMBL6305183 | 0.73 | — | — | |
| SCHEMBL1021333 | 0.73 | — | — | |
| SCHEMBL12917968 | 0.73 | — | — | |
| SCHEMBL2172456 | 0.72 | PIK3CD (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113795304-A | Thieno [3,2-B ] pyridin-7-amine compounds for the treatment of familial autonomic nervous dysfunction | PTC医疗公司 | 2021-12-14 | — | — | CN | disclosed |
| US-7589166-B2 | Thiophene-containing compound and polymer thereof | FUJI XEROX CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |