⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033555 | 0.82 | KDM4E (0.42) | — | |
| SCHEMBL1767952 | 0.82 | HRH4 (0.41) | — | |
| SCHEMBL15057849 | 0.79 | GABRA2 (0.38) | — | |
| SCHEMBL7982137 | 0.78 | — | — | |
| SCHEMBL1444830 | 0.77 | KCNH2 (0.41) | — | |
| SCHEMBL16340550 | 0.77 | NOS3 (0.40) | — | |
| SCHEMBL374273 | 0.76 | — | — | |
| SCHEMBL1660131 | 0.76 | — | — | |
| SCHEMBL4536920 | 0.76 | — | — | |
| SCHEMBL1661258 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986553-B1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20260028365-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12466804-B2 | Cyclobutyl carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-11-11 | — | — | US | disclosed |
| EP-4543890-A1 | USP1 INHIBITORS AND USES THEREOF | Forma Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731178-A | USP1 inhibitors and uses thereof | 福马治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240317725-A1 | LPA1 SMALL MOLECULE ANTAGONIST | TUOJIE BIOTECH (SHANGHAI) CO., LTD. (CN) | 2024-09-26 | — | — | US | disclosed |
| CN-112055711-B | Cyclohexylic acid triazolazine as LPA antagonist | 百时美施贵宝公司 | 2024-07-23 | — | — | CN | disclosed |
| US-20240228488-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-11 | — | — | US | disclosed |
| EP-4375277-A1 | LPA1 SMALL MOLECULE ANTAGONIST | Tuojie Biotech (Shanghai) Co., Ltd. (CN) | 2024-05-29 | — | — | EP | disclosed |
| US-20240124444-A1 | Heterocyclic Compounds and Their Use for Parasitic Diseases | CELGENE CORPORATION (US) | 2024-04-18 | — | — | US | disclosed |
| US-5688791-A | COMPOUNDS FOR TREATMENNT OF VIRAL DISEASES SUCH AS AIDS | UBE INDUSTRIES, LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0470600-B1 | Naphthylalkylaminopyrimidine derivatives, process for their preparation and pesticides containing them | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| WO-1997006160-A1 | PREPARATION OF TRIAZOLES BY ORGANOMETALLIC ADDITION TO KETONES AND INTERMEDIATES THEREFOR | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-02-20 | — | — | WO | disclosed |
| WO-1997001552-A1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-01-16 | — | — | WO | disclosed |
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| US-5468751-A | Aminopyrimidine derivatives as microbicides, insecticides and acaricides | CIBA-GEIGY CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| CN-1086515-A | Aminoquinolone derivative and anti-hiv agent that aryl or fragrant heterocyclic radical replace | UBE INDUSTRIES (JP) | 1994-05-11 | — | — | CN | disclosed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |
| WO-1993022291-A1 | ARTHROPODICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
| EP-0470600-A1 | Naphthylalkylaminopyrimidine derivatives, process for their preparation and pesticides containing them | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |