SCHEMBL1370831

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL1370171	0.99	HDAC1 (0.46)	HDAC1HDAC2HTTMAPK1TAAR1
	SCHEMBL1372970	0.90	AURKA (0.45)	HDAC1HDAC2MAPK1TSHRCYP1A2
	Hydrochloric Acid SCHEMBL1370666	0.89	AURKA (0.44)	HDAC1HDAC2MAPK1TSHRCYP1A2
	SCHEMBL1369867	0.82	XDH (0.44)	HDAC1HDAC2HTTTSHRLMNA
	SCHEMBL2623137	0.82	NAMPT (0.50)	MAPK1TSHRHSD17B10NPSR1SMN1; SMN2
	Hydrochloric Acid SCHEMBL1371882	0.81	XDH (0.43)	HDAC1HDAC2HTTTSHRLMNA
	SCHEMBL1369301	0.81	XDH (0.42)	HDAC1HDAC2HTTTSHRHSD17B10
	Hydrochloric Acid SCHEMBL1369764	0.80	XDH (0.41)	HDAC1HDAC2HTTTSHRHSD17B10
	SCHEMBL1369225	0.79	XDH (0.41)	HDAC1HDAC2TSHRLMNACA1
	SCHEMBL1371416	0.78	XDH (0.41)	HDAC1HDAC2HTTTSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.