Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10105029 | 0.74 | GRIA1 (0.42) | GRIA1GRIA2GRIA4GRIK5DAO | |
| SCHEMBL12603804 | 0.73 | SQOR (0.42) | GRIA1GRIA2GRIA4GRIK5DAO | |
| SCHEMBL15563493 | 0.73 | DAO (0.38) | GRIA1GRIA2GRIA4GRIK5DAO | |
| SCHEMBL12702610 | 0.73 | DAO (0.38) | DAOATMCYP3A4MAPK1PMP22 | |
| SCHEMBL16131591 | 0.73 | GRIA1 (0.41) | GRIA1GRIA2GRIA4GRIK5DAO | |
| SCHEMBL24419029 | 0.73 | DAO (0.38) | GRIA1GRIA2GRIA4GRIK5DAO | |
| SCHEMBL22743704 | 0.70 | ATM (0.46) | DAOATMCYP3A4MAPK1PMP22 | |
| SCHEMBL21840374 | 0.70 | DAO (0.35) | DAOATMCYP3A4MAPK1PMP22 | |
| SCHEMBL22743701 | 0.69 | ATM (0.35) | DAOATM | |
| SCHEMBL22743552 | 0.68 | DAO (0.34) | DAOATMCYP3A4MAPK1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115927-A2 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE | INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) | 2009-09-24 | — | — | WO | disclosed |