Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767648 | 0.75 | ATM (0.36) | ATM | |
| SCHEMBL12702610 | 0.72 | DAO (0.38) | DAOATMCYP3A4MAPK1PMP22 | |
| SCHEMBL22743701 | 0.72 | ATM (0.35) | DAOATM | |
| SCHEMBL10105029 | 0.70 | GRIA1 (0.42) | DAOATML3MBTL1 | |
| SCHEMBL24419029 | 0.68 | DAO (0.38) | DAOATMGAACYP3A4MAPK1 | |
| SCHEMBL16131591 | 0.68 | GRIA1 (0.41) | DAOATMCYP3A4MAPK1PMP22 | |
| SCHEMBL13708317 | 0.68 | GRIA1 (0.41) | DAOATMCYP3A4MAPK1PMP22 | |
| SCHEMBL12603804 | 0.68 | SQOR (0.42) | DAOATMGAACYP3A4MAPK1 | |
| SCHEMBL15563493 | 0.68 | DAO (0.38) | DAOATMCYP3A4MAPK1PMP22 | |
| SCHEMBL22743640 | 0.68 | DAO (0.34) | DAOATMPDE2ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239076-A1 | PYRIDAZINONE DERIVATIVES AS THYROXINE RECEPTOR-Β AGONISTS AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2020-12-03 | — | — | WO | disclosed |