Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 8/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708585 | 0.93 | SLC9A1 (0.37) | SLC9A1HTR6CNR2CNR1CYP11B1 | |
| SCHEMBL6275044 | 0.86 | BACE1 (0.34) | SLC9A1HTR6CYP11B1CYP11B2BACE1 | |
| SCHEMBL13079029 | 0.86 | BACE1 (0.34) | SLC9A1HTR6CYP11B1CYP11B2BACE1 | |
| SCHEMBL4467104 | 0.86 | FFAR4 (0.40) | CYP11B1CYP11B2LIPCLIPGKDM2B | |
| SCHEMBL13708607 | 0.84 | SCN5A (0.34) | SLC9A1HTR6CNR2BACE1 | |
| SCHEMBL13708618 | 0.84 | SLC9A1 (0.40) | SLC9A1CYP11B1CYP11B2 | |
| SCHEMBL13708560 | 0.83 | CACNA1B (0.35) | SLC9A1CNR2CYP11B1CYP11B2ICMT | |
| SCHEMBL4473805 | 0.83 | CYP11B1 (0.35) | CNR2CYP11B1CYP11B2LIPCLIPG | |
| SCHEMBL4473718 | 0.83 | CYP11B1 (0.35) | CNR2CYP11B1CYP11B2LIPCLIPG | |
| SCHEMBL4473169 | 0.83 | CYP11B1 (0.35) | CNR2CYP11B1CYP11B2LIPCLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589117-B2 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-7589117-B2 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-09-15 | — | — | US | disclosed |