Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.30 |
| ▸ | RAB9A | P51151 | 4/20 | 0.30 |
| ▸ | MITF | O75030 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708982 | 0.94 | PDK2 (0.38) | KIF11PDK2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13709017 | 0.89 | PDK2 (0.41) | KIF11PDK2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25596251 | 0.88 | PDK2 (0.47) | KIF11PDK2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5355996 | 0.85 | PDK2 (0.39) | PDK2KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4403113 | 0.82 | CA1 (0.41) | PDK2KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3178700 | 0.82 | PDK2 (0.45) | PDK2KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29524103 | 0.82 | PDK2 (0.45) | PDK2KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22745012 | 0.82 | PDK2 (0.40) | PDK2KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL679067 | 0.82 | PDK2 (0.40) | PDK2KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL431232 | 0.81 | KIF11 (0.37) | KIF11PDK2KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558696-B1 | NEW METHOD FOR THE PRODUCTION OF MONOMERS USEFUL IN THE MANUFACTURE OF SEMICONDUCTIVE POLYMERS | MERCK PATENT GMBH (DE) | 2009-09-23 | — | — | EP | disclosed |
| US-7368616-B2 | Method for the production of monomers useful in the manufacture of semiconductive polymers | MERCK PATENT GMBH (DE) | 2008-05-06 | — | — | US | disclosed |
| US-7368616-B2 | Method for the production of monomers useful in the manufacture of semiconductive polymers | MERCK PATENT GMBH (DE) | 2008-05-06 | — | — | US | disclosed |