Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 3/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521000 | 0.94 | PDK2 (0.42) | PDK2TDP2S100A4KDM4EMEN1 | |
| SCHEMBL12635475 | 0.91 | MAPK1 (0.48) | PDK2ALDH1A1MAPK1TDP2KDM4E | |
| SCHEMBL5359737 | 0.89 | PDK2 (0.38) | PDK2ALDH1A1TDP2MEN1LMNA | |
| SCHEMBL12781938 | 0.88 | MAPK1 (0.45) | PDK2ALDH1A1MAPK1TDP2KDM4E | |
| SCHEMBL16922978 | 0.88 | MAPK1 (0.45) | PDK2ALDH1A1MAPK1TDP2KDM4E | |
| SCHEMBL16922977 | 0.86 | MEN1 (0.47) | PDK2ALDH1A1MAPK1TDP2KDM4E | |
| SCHEMBL13708952 | 0.85 | KIF11 (0.37) | PDK2ALDH1A1TDP2KDM4EMEN1 | |
| SCHEMBL16922981 | 0.84 | MAPK1 (0.45) | PDK2ALDH1A1MAPK1TDP2KDM4E | |
| SCHEMBL13414972 | 0.84 | ALDH1A1 (0.50) | PDK2ALDH1A1MAPK1TDP2KDM4E | |
| SCHEMBL3176035 | 0.84 | ALDH1A1 (0.41) | PDK2ALDH1A1MAPK1TDP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189877-B2 | Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSCH CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| US-7189877-B2 | Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSCH CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| US-7189877-B2 | Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSCH CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1400578-B1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | TOSOH CORP (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSOH CORPORATION | 2004-06-10 | — | — | US | disclosed |
| EP-1400578-A1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | Tosoh Corporation (JP) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | AHR, NAT1, AR | PDK2 2093/4885ALDH1A1 132/4885MAPK1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.