Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550663 | 0.85 | KIF11 (0.45) | TSHRHSD17B10KIF11CYP2A6BLM | |
| SCHEMBL17066853 | 0.84 | KIF11 (0.44) | TSHRHSD17B10KIF11CYP2A6BLM | |
| SCHEMBL539357 | 0.82 | PPARA (0.45) | TSHRHSD17B10KIF11BLMMMP12 | |
| SCHEMBL539358 | 0.82 | PPARA (0.45) | TSHRHSD17B10KIF11BLMMMP12 | |
| SCHEMBL8694396 | 0.80 | BLM (0.65) | HSD17B10CYP2A6BLMRAB9APPARA | |
| SCHEMBL25058399 | 0.78 | KIF11 (0.53) | TSHRHSD17B10KIF11CYP2A6LOXL2 | |
| SCHEMBL5201387 | 0.77 | SMN1; SMN2 (0.42) | TSHRCYP2A6BLMRAB9AEPHX2 | |
| SCHEMBL5201384 | 0.77 | SMN1; SMN2 (0.42) | TSHRCYP2A6BLMRAB9AEPHX2 | |
| SCHEMBL5201595 | 0.77 | SMN1; SMN2 (0.42) | TSHRCYP2A6BLMRAB9AEPHX2 | |
| SCHEMBL12923161 | 0.75 | SLC6A2 (0.53) | HSD17B10BLMPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111700-A2 | OXADIAZOANTHRACENE COMPOUNDS FOR THE TREATMENT OF DIABETES | TRANSTECH PHARMA, INC. (US) | 2009-09-11 | — | — | WO | disclosed |