Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201595 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTTSHRCYP2A6LMNA | |
| SCHEMBL5201384 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTTSHRCYP2A6LMNA | |
| SCHEMBL29277106 | 0.82 | CYP2A6 (0.44) | SMN1; SMN2MAPTTSHRCYP2A6LMNA | |
| SCHEMBL9386400 | 0.82 | BLM (0.63) | SMN1; SMN2MAPTTSHRBLMCNR2 | |
| SCHEMBL9386398 | 0.82 | BLM (0.63) | SMN1; SMN2MAPTTSHRBLMCNR2 | |
| SCHEMBL539357 | 0.82 | PPARA (0.45) | MAPTTSHRBLMEPHX2LOXL2 | |
| SCHEMBL539358 | 0.82 | PPARA (0.45) | MAPTTSHRBLMEPHX2LOXL2 | |
| SCHEMBL5205923 | 0.81 | MMP8 (0.48) | SMN1; SMN2MAPTTSHRLMNABLM | |
| SCHEMBL6974147 | 0.81 | MMP8 (0.48) | SMN1; SMN2MAPTTSHRLMNABLM | |
| SCHEMBL1773480 | 0.81 | CYP3A4 (0.55) | SMN1; SMN2MAPTTSHRLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284973-B1 | INHIBITORS OF ALPHA L BETA 2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-6699888-B2 | ANTIINFLAMMATORY | TANABE SEIYAKU CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20030225138-A1 | Inhibitors of alpha l beta 2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2003-12-04 | — | — | US | disclosed |
| EP-1284973-A2 | INHIBITORS OF ALPHA L BETA 2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092253-A2 | INHIBITORS OF ALPHA L BETA 2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225138-A1 | Inhibitors of alpha l beta 2 mediated cell adhesion | ICAM1, VCAM1, SELL | SMN1; SMN2 3716/4885MAPT 2961/4885TSHR 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.