Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | RXRB | P28702 | 4/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312413 | 0.91 | RXRA (0.51) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709252 | 0.87 | HTT (0.43) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709240 | 0.86 | RXRA (0.43) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709243 | 0.86 | RXRA (0.43) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709393 | 0.84 | PTGER2 (0.53) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709220 | 0.83 | RXRA (0.40) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709251 | 0.83 | RXRA (0.45) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709242 | 0.79 | RXRA (0.46) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709250 | 0.79 | RXRA (0.43) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13312425 | 0.78 | RXRA (0.51) | RXRARXRBRXRGPTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |