Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.43 |
| ▸ | RXRB | P28702 | 5/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13709251 | 0.92 | RXRA (0.45) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13312527 | 0.90 | RXRA (0.55) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709393 | 0.90 | PTGER2 (0.53) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709240 | 0.90 | RXRA (0.43) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709242 | 0.86 | RXRA (0.46) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709232 | 0.86 | RXRA (0.40) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709252 | 0.85 | HTT (0.43) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL3500903 | 0.83 | RXRA (0.49) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13709250 | 0.82 | RXRA (0.43) | RXRARXRBRXRGPTGER4PTGER2 | |
| SCHEMBL13312151 | 0.80 | RXRB (0.61) | RXRARXRBRXRGPTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |