Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786376 | 0.83 | DRD2 (0.47) | DRD2DRD4HTR7DRD3HTR2B | |
| SCHEMBL12426595 | 0.79 | MEN1 (0.43) | DRD2DRD4HTR7DRD3HTR2B | |
| SCHEMBL12786238 | 0.77 | DRD2 (0.34) | DRD2DRD4HTR7DRD3HTR2B | |
| SCHEMBL13317746 | 0.77 | DRD2 (0.34) | DRD2DRD4HTR7DRD3HTR2B | |
| SCHEMBL12599868 | 0.77 | CYP1A2 (0.49) | DRD4HTR2BALDH1A1HSD17B10MAPT | |
| SCHEMBL811240 | 0.75 | TSHR (0.38) | DRD2DRD4HTR7DRD3HTR2B | |
| SCHEMBL12599382 | 0.70 | MC4R (0.44) | — | |
| SCHEMBL29716676 | 0.69 | TSHR (0.52) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL868639 | 0.69 | TSHR (0.52) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL19797772 | 0.69 | TMEM97 (0.40) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2095875-A1 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2009-09-02 | — | — | EP | disclosed |