SCHEMBL868639

SCHEMBL868639

c1ccc2c3c(ccc2c1)Cc1ccc2ccccc2c1-3

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
CYP2A6 P11509 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
HPRT1 P00492 1/20 0.48
MAPT P10636 1/20 0.45
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
WDR5 P61964 1/20 0.43
CYP3A4 P08684 1/20 0.42
DNMT1 P26358 1/20 0.42
ANPEP P15144 1/20 0.42
CES1 P23141 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.39
CYP1A2 P05177 1/20 0.39
PAX8 Q06710 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29716676 1.00 TSHR (0.52) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL21385140 0.98 TSHR (0.50) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL15769977 0.89 TSHR (0.45) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL15769432 0.86 TSHR (0.52) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL29520144 0.85 DNMT1 (0.44) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL867598 0.85 DNMT1 (0.44) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL4855064 0.83 MAPT (0.41) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL6987200 0.82 DNMT1 (0.46) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL14452850 0.82 PARP1 (0.41) TSHRCYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL17063439 0.82 ALDH1A1 (0.35) TSHRCYP2A6ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291342-B1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KK (JP) 2014-06-04 EP claimed
US-8431249-B2 Dibenzo[C,G]fluorene compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2013-04-30 US claimed
US-8377574-B2 Dibenzo[c,g]fluorene compound and an organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2013-02-19 US claimed
US-20110260150-A1 DIBENZO[C,G]FLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2011-10-27 US claimed
US-7964722-B2 Light-driven rotary molecular motors BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-06-21 US claimed
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS NATIONAL SCIENCE FOUNDATION 2011-03-31 US claimed
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-02-24 US claimed
US-12187824-B2 Polyolefin and method for preparing same Hanwha Solutions Corporation (KR) 2025-01-07 US disclosed
EP-3896102-B1 POLYOLEFIN AND METHOD FOR PREPARING SAME HANWHA SOLUTIONS CORP (KR) 2024-11-06 EP disclosed
CN-111836836-B Transition metal compound for olefin polymerization catalyst, catalyst and polyolefin polymerized by using the catalyst 韩华思路信株式会社 2023-04-28 CN disclosed
EP-4141979-A1 ORGANIC LIGHT EMITTING DIODE AND A COMPOUND FOR USE THEREIN Novaled GmbH (DE) 2023-03-01 EP disclosed
US-11555028-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2023-01-17 US disclosed
US-11384108-B2 Transition metal compound for olefin polymerization catalyst, olefin polymerization catalyst including same, and polyolefin polymerized by using olefin polymerization catalyst Hanwha Solutions Corporation (KR) 2022-07-12 US disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed
US-5770664-A Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst JAPAN POLYOLEFINS CO., LTD. (JP) 1998-06-23 US disclosed
EP-0707016-B1 Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst JAPAN POLYOLEFINS CO LTD (JP) 1997-09-24 EP disclosed
EP-0707016-A1 Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst JAPAN POLYOLEFINS CO., LTD. (JP) 1996-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384108-B2 Transition metal compound for olefin polymerization catalyst, olefin polymerization catalyst including same, and polyolefin polymerized by using olefin polymerization catalyst ODC1, PPOX, MOGAT2 TSHR 4780/4885CYP2A6 941/4885ALDH1A1 341/4885
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS CCNA2, CCNO, SCO2 TSHR 752/4885CYP2A6 3535/4885ALDH1A1 4255/4885
US-11555028-B2 Organic compound and photoelectric conversion element SCN2B, MRPS22, CTNNA1 TSHR 3018/4885CYP2A6 579/4885ALDH1A1 908/4885
US-20110260150-A1 DIBENZO[C,G]FLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME GNG2, RARG, FRG1 TSHR 3531/4885CYP2A6 2278/4885ALDH1A1 2076/4885
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME LEF1, GNG2, SCO2 TSHR 4121/4885CYP2A6 1363/4885ALDH1A1 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.