Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761083 | 0.79 | HRH3 (0.43) | HRH3KDM4ECNR1MAPK1TSHR | |
| SCHEMBL13712411 | 0.79 | APEX1 (0.37) | HRH3KDM4EMAPTPOLBNPC1 | |
| SCHEMBL13710231 | 0.73 | HRH3 (0.46) | HRH3KDM4ECNR1MAPK1TSHR | |
| SCHEMBL13710244 | 0.70 | LMNA (0.46) | HRH3KDM4ELMNAMAPTPOLB | |
| SCHEMBL14064299 | 0.68 | SLC2A1 (0.41) | HRH3KDM4ETSHRLMNAMAPT | |
| SCHEMBL13710228 | 0.65 | RARA (0.46) | KDM4ELMNAMAPTPOLBNPC1 | |
| SCHEMBL13761086 | 0.65 | MAPT (0.44) | HRH3LMNAMAPTPOLB | |
| SCHEMBL14064298 | 0.64 | APEX1 (0.40) | HRH3KDM4ECNR1MAPK1LMNA | |
| SCHEMBL5649433 | 0.63 | SMN1; SMN2 (0.53) | KDM4EMAPK1TSHRLMNAMAPT | |
| SCHEMBL13710241 | 0.63 | KMT2A (0.42) | HRH3KDM4ELMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595404-B2 | Thiazolyl-substituted carbocyclic 1,3-diones as pesticidal agents | BAYER CROPSCIENCE AG (DE) | 2009-09-29 | — | — | US | disclosed |
| US-7595404-B2 | Thiazolyl-substituted carbocyclic 1,3-diones as pesticidal agents | BAYER CROPSCIENCE AG (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | DDT, CYP4B1, CYP1B1 | HRH3 2958/4885KDM4E 1623/4885CNR1 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.