Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962842 | 0.86 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL3680400 | 0.86 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL15337 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL396824 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL18169552 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL8965833 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL19197808 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL51592 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1171384 | 0.83 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL6249922 | 0.82 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790353-A | SILICONE HYDROGELS COMPRISING POLYAMIDES | 庄臣及庄臣视力保护公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109415474-A | SILICONE HYDROGELS COMPRISING HIGH LEVELS OF POLYAMIDES | 庄臣及庄臣视力保护公司 | 2019-03-01 | — | — | CN | claimed |
| US-20170348219-A1 | COPOLYMER AND OILY GELLING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2017-12-07 | — | — | US | claimed |
| EP-3235839-A1 | COPOLYMER AND OILY GELLING AGENT | Shiseido Company Ltd. (JP) | 2017-10-25 | — | — | EP | claimed |
| CN-107250181-A | Copolymer and oil gelling agent | 株式会社资生堂 | 2017-10-13 | — | — | CN | claimed |
| CN-104114612-B | Silicone hydrogels containing desirable water content and oxygen permeability | 庄臣及庄臣视力保护公司 | 2017-09-26 | — | — | CN | claimed |
| CN-104144972-B | Ionic silicone hydrogels | 庄臣及庄臣视力保护公司 | 2017-07-21 | — | — | CN | claimed |
| CN-104144971-B | Silicone hydrogels formed from zero diluent reactive mixtures | 庄臣及庄臣视力保护公司 | 2017-03-15 | — | — | CN | claimed |
| CN-104114610-B | Silicone hydrogels with structures formed via controlled reaction kinetics | 庄臣及庄臣视力保护公司 | 2016-12-28 | — | — | CN | claimed |
| CN-104114611-B | Silicone hydrogels comprising N-vinylamides and hydroxyalkyl (meth) acrylates or (meth) acrylamides | 庄臣及庄臣视力保护公司 | 2016-11-16 | — | — | CN | claimed |
| US-8664350-B2 | Polymeric coupling agents | LUBRIZOL LIMITED (GB) | 2014-03-04 | — | — | US | claimed |
| CN-101541874-B | Polymeric coupling agents | LUBRIZOL LTD | 2013-04-03 | — | — | CN | claimed |
| US-20090306252-A1 | Polymeric Coupling Agents | LUBRIZOL LIMITED (GB) | 2009-12-10 | — | — | US | claimed |
| CN-101541874-A | Polymeric coupling agents | LUBRIZOL LTD (GB) | 2009-09-23 | — | — | CN | claimed |
| EP-2084219-A1 | POLYMERIC COUPLING AGENTS | Lubrizol Limited (GB) | 2009-08-05 | — | — | EP | claimed |
| US-20080258345-A1 | Liquid Radiation-Curing Compositions | STIFTUNG CAESAR (DE) | 2008-10-23 | — | — | US | claimed |
| WO-2008049840-A1 | POLYMERIC COUPLING AGENTS | LUBRIZOL LIMITED (GB) | 2008-05-02 | — | — | WO | claimed |
| CN-100378061-C | Vinyl polymerized monomer and polymer contg. tert-hydroxyl | MITSUBISHI GAS CHEMICAL CO (JP) | 2008-04-02 | — | — | CN | claimed |
| EP-1773901-A1 | LIQUID RADIATION-CURING COMPOSITIONS | Stiftung CAESAR (DE) | 2007-04-18 | — | — | EP | claimed |
| WO-2006005772-A1 | LIQUID RADIATION-CURING COMPOSITIONS | STIFTUNG CAESAR (DE) | 2006-01-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348219-A1 | COPOLYMER AND OILY GELLING AGENT | ELOVL6, MCM6, PTGER1 | TSHR 3768/4885THRB 3808/4885ALDH1A1 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.