Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368219 | 1.00 | MAOA (0.54) | MAOACYP3A4CYP2D6KCNH2MAOB | |
| SCHEMBL13335062 | 0.92 | MAOA (0.57) | MAOACYP3A4CYP2D6KCNH2MAOB | |
| SCHEMBL3368719 | 0.92 | MAOA (0.57) | MAOACYP3A4CYP2D6KCNH2MAOB | |
| SCHEMBL3369702 | 0.92 | MAOA (0.56) | MAOACYP3A4CYP2D6KCNH2MAOB | |
| SCHEMBL13711608 | 0.92 | MAOA (0.56) | MAOACYP3A4CYP2D6KCNH2MAOB | |
| SCHEMBL14012838 | 0.91 | MAOA (0.66) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3368752 | 0.91 | MAOA (0.66) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13711587 | 0.91 | MAOA (0.54) | MAOACYP3A4CYP2D6KCNH2MAOB | |
| SCHEMBL3367325 | 0.91 | MAOA (0.54) | MAOACYP3A4CYP2D6KCNH2 | |
| SCHEMBL13711589 | 0.91 | MAOA (0.54) | MAOACYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582659-B2 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO., INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-7462633-B2 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO., INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-20070203187-A1 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO., INC. (US) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203187-A1 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | OXA1L, ALAD, COASY | MAOA 2977/4885CYP3A4 117/4885CYP2D6 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.