Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30722024 | 0.84 | TSHR (0.60) | KDM4ETSHRHCAR2KEAP1NFE2L2 | |
| SCHEMBL31362035 | 0.83 | TSHR (0.41) | KDM4ETSHRMGAMGAASI | |
| SCHEMBL17243706 | 0.80 | KDM4E (0.36) | KDM4ETSHRMGAMGAASI | |
| SCHEMBL14478054 | 0.79 | KDM4E (0.65) | KDM4ETSHRMGAMGAASI | |
| SCHEMBL1669126 | 0.79 | KDM4E (0.46) | KDM4ETSHRMGAMGAASI | |
| SCHEMBL10071805 | 0.79 | KDM4E (0.65) | KDM4ETSHRMGAMGAASI | |
| SCHEMBL24180793 | 0.76 | KDM4E (0.43) | KDM4ETSHRMGAMGAASI | |
| SCHEMBL27674025 | 0.75 | TSHR (0.52) | KDM4ETSHRMGAMGAASI | |
| SCHEMBL9054271 | 0.75 | KDM4E (0.44) | KDM4ETSHRALOX15HSD17B10 | |
| SCHEMBL18470363 | 0.74 | KDM4E (0.41) | KDM4ETSHRMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592449-B2 | Structural carotenoid analogs for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-09-22 | — | — | US | disclosed |