Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478054 | 1.00 | KDM4E (0.65) | KDM4ETSHRKDM6BKDM5CEGLN1 | |
| SCHEMBL28942452 | 0.87 | TSHR (0.83) | KDM4ETSHREGLN1ATMGRIK1 | |
| SCHEMBL1669126 | 0.85 | KDM4E (0.46) | KDM4ETSHRKDM6BKDM5CEGLN1 | |
| Aconitic Acid SCHEMBL31252804 | 0.83 | KDM4E (0.86) | KDM4ETSHRKDM6BKDM5CEGLN1 | |
| SCHEMBL24180793 | 0.81 | KDM4E (0.43) | KDM4ETSHRKDM6BKDM5CEGLN1 | |
| SCHEMBL23794127 | 0.81 | KDM4E (0.60) | KDM4ETSHRATM | |
| Aconitic Acid SCHEMBL27092737 | 0.79 | TSHR (0.78) | KDM4ETSHRATM | |
| SCHEMBL13712337 | 0.79 | KDM4E (0.41) | KDM4ETSHRKDM6BKDM5CEGLN1 | |
| SCHEMBL18470363 | 0.79 | KDM4E (0.41) | KDM4ETSHRKDM6BKDM5CEGLN1 | |
| Aconitic Acid SCHEMBL219037 | 0.79 | TSHR (1.00) | KDM4ETSHRLMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884937-B2 | Polymer compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-02-06 | — | — | US | disclosed |
| US-9850345-B2 | Polycarbonate polyol compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-12-26 | — | — | US | disclosed |
| US-9834710-B2 | Adhesive compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-12-05 | — | — | US | disclosed |
| US-20170145147-A1 | HIGH STRENGTH POLYURETHANE FOAM COMPOSITIONS AND METHODS | NOVOMER, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170051106-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-02-23 | — | — | US | disclosed |
| US-20170022319-A1 | ALIPHATIC POLYCARBONATE POLYOL COMPOSITIONS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-01-26 | — | — | US | disclosed |
| US-9512259-B2 | High strength polyurethane foam compositions and methods | NOVOMER, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160319064-A1 | POLYMER COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-11-03 | — | — | US | disclosed |
| US-9453100-B2 | Polymer compositions and methods | NOVOMER, INC. (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160264728-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-09-15 | — | — | US | disclosed |
| US-20130281633-A1 | POLYMER COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130274401-A1 | ADHESIVE COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130244864-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130172482-A1 | POLYMER COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8470956-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20130066044-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2013001297-A1 | BINDING INHIBITORS OF THE BETA.TRANSDUCIN REPEAT - CONTAINING PROTEIN | ITI SCOTLAND LIMITED (GB) | 2013-01-03 | — | — | WO | disclosed |
| US-8247520-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| WO-2012046008-A2 | MATERIALS AND METHODS FOR INCREASING HSP20 ACTIVITY | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2012-04-12 | — | — | WO | disclosed |
| US-20110230580-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc (US) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230580-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | PARG, PUF60, PICALM | KDM4E 628/4885TSHR 4872/4885KDM6B 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.