Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | ESRRG | P62508 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304805 | 1.00 | ESR1 (0.59) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL15417635 | 0.95 | ESR2 (0.53) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL13712957 | 0.91 | ESR1 (0.67) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL7590568 | 0.90 | HPGD (0.41) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL21538673 | 0.87 | ESR1 (0.42) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL308378 | 0.84 | MEN1 (0.50) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL13447587 | 0.83 | SMN1; SMN2 (0.49) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL12329883 | 0.83 | ALDH1A1 (0.45) | HSD17B10ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12325325 | 0.83 | TSHR (0.41) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL9887145 | 0.83 | ESR1 (0.65) | ESR1ESR2CYP3A4ARHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582355-B2 | Optical unit using plastic lenses | FUJIFILM CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |