SCHEMBL308378

SCHEMBL308378

O=COc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ESR2 Q92731 2/20 0.50
ESR1 P03372 1/20 0.50
ALDH5A1 P51649 1/20 0.46
ABAT P80404 1/20 0.46
LTA4H P09960 3/20 0.42
NR1H2 P55055 1/20 0.42
BAX Q07812 1/20 0.42
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
TYR P14679 2/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42
GMNN O75496 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
LMNA P02545 1/20 0.42
CA3 P07451 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28128650 0.97 MEN1 (0.48) MEN1KMT2AESR2ESR1ALDH5A1
SCHEMBL13445852 0.93 MEN1 (0.64) MEN1KMT2AESR2ESR1ALDH5A1
SCHEMBL2612608 0.93 ESR2 (0.52) MEN1KMT2AESR2ESR1ALDH5A1
Sulfurous Acid SCHEMBL11594095 0.91 MEN1 (0.42) MEN1KMT2AESR2ESR1ALDH5A1
Formic Acid Phenyl Ester SCHEMBL28750205 0.88 LTA4H (0.54) MEN1KMT2AESR2ESR1ALDH5A1
SCHEMBL25677973 0.87 KMT2A (0.48) MEN1KMT2AESR2ESR1MAPT
SCHEMBL12582319 0.87 NR1H2 (0.56) MEN1KMT2AESR2ESR1ALDH5A1
SCHEMBL12738601 0.87 ESR1 (0.56) MEN1KMT2AESR2ESR1ALDH5A1
SCHEMBL6454577 0.86 ALDH1A1 (0.38) KDM4EALDH1A1TYRCA12CA1
SCHEMBL13712969 0.84 ESR1 (0.59) MEN1KMT2AESR2ESR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117138842-A Phenolic resin-based composite photocatalyst and preparation method and application thereof 江苏大学 2023-12-01 CN claimed
CN-110637007-B9 Synthesis of tyrosine-derived diphenol monomers 美敦力公司 2023-08-15 CN claimed
CN-110637007-B Synthesis of tyrosine-derived diphenol monomers 美敦力公司 2023-06-16 CN claimed
CN-115991861-A Damping fatigue aging resistant carbon dioxide-based polyurethane elastomer and preparation method thereof 河北铁科翼辰新材科技有限公司 2023-04-21 CN claimed
EP-3634944-B1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS MEDTRONIC INC (US) 2022-06-29 EP claimed
US-10868297-B2 Secondary battery comprising a carbon-silicon composite electrode and method of preparing same Sogang University Research Foundation (KR) 2020-12-15 US claimed
EP-3634944-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS Medtronic, Inc. (US) 2020-04-15 EP claimed
CN-110637007-A Synthesis of tyrosine-derived diphenol monomers 美敦力公司 2019-12-31 CN claimed
US-10442757-B2 Synthesis of tyrosine derived diphenol monomers MEDTRONIC, INC. (US) 2019-10-15 US claimed
US-20180354892-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYRX, INC. (US) 2018-12-13 US claimed
CN-105062469-A Six-nuclear cyclotriphosphazene terbium complex light-emitting material and preparation method thereof UNIV CHONGQING TECHNOLOGY 2015-11-18 CN claimed
CN-104600307-A Preparation method of multiwalled carbon nanotube for lithium air battery positive electrode UNIV SHANGHAI JIAOTONG 2015-05-06 CN claimed
US-RE37160-E1 COUPLING A HYDROXYPHENYL CARBOXYLIC ACID WITH AN L-TYROSINE ESTER IN A WATER-MISCIBLE ORGANIC REACTION SOLVENT CONTAINING A CARBODIIMIDE CAPABLE OF FORMING A WATER-SOLVENT UREA BY-PRODUCT RUTGERS, THE STATE UNIVERSITY 2001-05-01 US claimed
EP-0824513-B1 IMPROVED SYNTHESIS OF TYROSINE-DERIVED DIPHENOL MONOMERS UNIV RUTGERS (US) 2000-07-19 EP claimed
EP-0824513-A1 IMPROVED SYNTHESIS OF TYROSINE-DERIVED DIPHENOL MONOMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 1998-02-25 EP claimed
EP-0824513-A4 1998-02-25 EP claimed
US-5587507-A PURIFICATION BY FORMING WATER SOLUBLE UREA BY-PRODUCT RUTGERS, THE STATE UNIVERSITY (US) 1996-12-24 US claimed
WO-1996030331-A1 IMPROVED SYNTHESIS OF TYROSINE-DERIVED DIPHENOL MONOMERS RUTGERS, THE STATE UNIVERSITY (US) 1996-10-03 WO claimed
US-4886624-A STABLE; DRIERS RHONE-POULENC, INC. (US) 1989-12-12 US claimed
US-4609691-A CHAIN EXTENSION WITH ELASTICIZED BASF FARBEN & FASERN AG (DE) 1986-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10442757-B2 Synthesis of tyrosine derived diphenol monomers TYR, TH, TYRO3 MEN1 2812/4885KMT2A 1377/4885ESR2 1456/4885
US-20180354892-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYR, TH, DDT MEN1 3324/4885KMT2A 1339/4885ESR2 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.