Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18782614 | 1.00 | PGR (0.38) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13188073 | 1.00 | PGR (0.38) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL12980219 | 0.79 | FDPS (0.38) | FDPS | |
| SCHEMBL12980411 | 0.79 | FDPS (0.38) | FDPS | |
| SCHEMBL25900127 | 0.77 | KDM5A (0.30) | — | |
| SCHEMBL3889876 | 0.77 | PGR (0.40) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL12980012 | 0.76 | PGR (0.36) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL12980221 | 0.76 | PGR (0.36) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13267240 | 0.76 | PGR (0.36) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL12367996 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |