Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933397 | 0.90 | MAPK1 (0.50) | MAPK1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL22967693 | 0.84 | MAPK1 (0.52) | MAPK1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL12963500 | 0.83 | F2 (0.51) | MAPK1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL21340438 | 0.79 | MAPK1 (0.56) | MAPK1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL12963727 | 0.79 | ACACB (0.50) | MAPK1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL13930972 | 0.79 | MAPK1 (0.49) | MAPK1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL28048524 | 0.78 | MAPK1 (0.64) | MAPK1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10212096 | 0.76 | RAB9A (0.58) | MAPK1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL8361588 | 0.76 | MAPK1 (0.58) | MAPK1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL22874652 | 0.76 | MAPK1 (0.52) | MAPK1MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |