Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340438 | 0.84 | MAPK1 (0.56) | MAPK1ACACBMEN1KMT2ARAB9A | |
| SCHEMBL12963727 | 0.83 | ACACB (0.50) | MAPK1ACACBMEN1KMT2ARAB9A | |
| SCHEMBL28048524 | 0.83 | MAPK1 (0.64) | MAPK1ACACBMEN1KMT2ARAB9A | |
| SCHEMBL6958985 | 0.82 | F2 (0.49) | RAB9AADAMTS4MMP13SMN1; SMN2GAA | |
| SCHEMBL7468581 | 0.82 | LTA4H (0.58) | MEN1KMT2ARAB9AALDH1A1TP53 | |
| SCHEMBL18997950 | 0.81 | SMN1; SMN2 (0.53) | MAPK1ACACBRAB9AADAMTS4GPR132 | |
| SCHEMBL22967693 | 0.80 | MAPK1 (0.52) | MAPK1ACACBMEN1KMT2ARAB9A | |
| SCHEMBL7255986 | 0.80 | CRHBP (0.54) | MAPK1ACACBMEN1KMT2ARAB9A | |
| SCHEMBL2736161 | 0.79 | ACACB (0.60) | MAPK1ACACBADAMTS4GPR132ALDH1A1 | |
| SCHEMBL7260691 | 0.79 | KMT2A (0.64) | MAPK1ACACBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760633-B1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2021-12-15 | — | — | EP | disclosed |
| EP-3760633-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-01-06 | — | — | EP | disclosed |