SCHEMBL137145

SCHEMBL137145

O=C(O)c1cc(/N=N/c2ccccc2)ccc1O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.85
KMT2A Q03164 6/20 0.85
BLVRB P30043 2/20 0.85
PDE4A P27815 1/20 0.85
KDR P35968 1/20 0.85
HTT P42858 1/20 0.85
TDP1 Q9NUW8 4/20 0.80
APP P05067 1/20 0.80
THRB P10828 1/20 0.80
RECQL P46063 1/20 0.80
BLM P54132 1/20 0.80
ALDH1A1 P00352 3/20 0.69
PHLPP2 Q6ZVD8 2/20 0.69
CYP2C9 P11712 2/20 0.69
TSHR P16473 2/20 0.69
PTGS2 P35354 2/20 0.69
PTGS1 P23219 1/20 0.69
HSD17B10 Q99714 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2C19 P33261 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15339774 1.00 MEN1 (0.85) MEN1KMT2ABLVRBPDE4AKDR
SCHEMBL137146 1.00 MEN1 (0.85) MEN1KMT2ABLVRBPDE4AKDR
SCHEMBL28847216 0.98 MEN1 (0.82) MEN1KMT2ABLVRBPDE4AKDR
Olsalazine SCHEMBL29861404 0.92 MEN1 (1.00) MEN1KMT2ABLVRBPDE4AKDR
Olsalazine SCHEMBL29385751 0.92 MEN1 (1.00) MEN1KMT2ABLVRBPDE4AKDR
Olsalazine SCHEMBL2628413 0.92 MEN1 (1.00) MEN1KMT2ABLVRBPDE4AKDR
Olsalazine SCHEMBL25119 0.92 MEN1 (1.00) MEN1KMT2ABLVRBPDE4AKDR
Olsalazine SCHEMBL25118 0.92 MEN1 (1.00) MEN1KMT2ABLVRBPDE4AKDR
Olsalazine SCHEMBL29378994 0.92 MEN1 (1.00) MEN1KMT2ABLVRBPDE4AKDR
Olsalazine SCHEMBL29769 0.90 MEN1 (0.96) MEN1KMT2ABLVRBPDE4AKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7563753-B2 Cleaning solution for removing photoresist HYNIX SEMICONDUCTOR INC. (KR) 2009-07-21 US claimed
EP-0738152-B1 USE OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES AS COLON CANCER CHEMOPREVENTATIVE AND CHEMOTHERAPEUTIC AGENTS SALIX PHARMACEUTICALS INC (US) 2005-11-02 EP claimed
US-5905073-A ANTICARCINOGENIC AGENTS SALIX PHARMACEUTICALS, INC. (US) 1999-05-18 US claimed
US-5498608-A Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents SALIX PHARMACEUTICALS (US) 1996-03-12 US claimed
US-4412992-A 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith BIOREX LABORATORIES LIMITED (GB) 1983-11-01 US claimed
US-20230321096-A1 COMPOSITION FOR IMPROVING, PREVENTING OR TREATING MUSCULAR DISORDERS INCLUDING SULFONAMIDE-BASED COMPOUNDS THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) 2023-10-12 US disclosed
EP-2096912-B1 FORMULATIONS AND USES OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES SALIX PHARMACEUTICALS INC (US) 2018-05-30 EP disclosed
EP-2563117-B1 FORMULATIONS AND USES OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES FOR THE TREATMENT OF MALES SALIX PHARMACEUTICALS LTD (US) 2018-02-21 EP disclosed
US-20170333458-A1 PREVENTION, TREATMENT, AND AMELIORATION OF RADIATION INDUCED ENTERITIS TECHNOLAS PERFECT VISION GMBH (DE) 2017-11-23 US disclosed
EP-2978416-B1 PHARMACEUTICAL FORMULATION COMPRISING PHOSPHATIDYLCHOLINE FOR THE TREATMENT OF ULCERATIVE COLITIS LIPID THERAPEUTICS GMBH (DE) 2016-10-26 EP disclosed
US-20160120886-A1 PREVENTION, TREATMENT, AND AMELIORATION OF RADIATION INDUCED ENTERITIS Salix Pharmaceuticals, Ltd 2016-05-05 US disclosed
US-20160045523-A1 PHARMACEUTICAL FORMULATION COMPRISING PHOSPHATIDYLCHOLINE FOR THE TREATMENT OF ULCERATIVE COLITIS LIPID THERAPEUTICS GMBH (DE) 2016-02-18 US disclosed
US-5498608-A Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents SALIX PHARMACEUTICALS (US) 1996-03-12 US disclosed
US-5498608-A Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents SALIX PHARMACEUTICALS (US) 1996-03-12 US disclosed
WO-1995018622-A1 USE OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES AS COLON CANCER CHEMOPREVENTATIVE AND CHEMOTHERAPEUTIC AGENTS SALIX PHARMACEUTICALS, INC. (US) 1995-07-13 WO disclosed
EP-0203122-B1 A PROCESS FOR PREPARING P-AMINO PHENOLS BY ELECTROLYSIS FARMACEUTISK LABORATORIUM FERRING A/S (DK) 1989-04-26 EP disclosed
US-4670112-A USING P-PHENYLAZOPHENALS FARMACEUTISK LABORATORIUM FERRING A/S (DK) 1987-06-02 US disclosed
EP-0203122-A1 A PROCESS FOR PREPARING p-AMINO PHENOLS BY ELECTROLYSIS. FERRING FARMA LAB (DK) 1986-12-03 EP disclosed
WO-1986003194-A1 A PROCESS FOR PREPARING p-AMINO PHENOLS BY ELECTROLYSIS FARMACEUTISK LABORATORIUM FERRING A/S (DK) 1986-06-05 WO disclosed
US-4412992-A 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith BIOREX LABORATORIES LIMITED (GB) 1983-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321096-A1 COMPOSITION FOR IMPROVING, PREVENTING OR TREATING MUSCULAR DISORDERS INCLUDING SULFONAMIDE-BASED COMPOUNDS PHF20, MYH10, MYOF MEN1 4446/4885KMT2A 487/4885BLVRB 4147/4885
US-20160045523-A1 PHARMACEUTICAL FORMULATION COMPRISING PHOSPHATIDYLCHOLINE FOR THE TREATMENT OF ULCERATIVE COLITIS LPAR1, FFAR1, LPAR2 MEN1 4022/4885KMT2A 3450/4885BLVRB 2420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.