SCHEMBL13714848

SCHEMBL13714848

C=CC(=O)OCCNC(=O)OCCOc1ccc(C2(c3ccc(OCCOC(=O)NCCOC(=O)C=C)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
PDK2 Q15119 3/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RAB9A P51151 4/20 0.38
NPC1 O15118 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
LMNA P02545 2/20 0.37
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.36
HRH3 Q9Y5N1 2/20 0.35
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.33
TGM2 P21980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30466297 1.00 THRB (0.52) THRBPDK2MAPTL3MBTL1RAB9A
SCHEMBL20411188 0.98 THRB (0.53) THRBPDK2MAPTL3MBTL1RAB9A
SCHEMBL25784675 0.95 THRB (0.47) THRBPDK2MAPTL3MBTL1RAB9A
SCHEMBL29368072 0.90 THRB (0.63) THRBPDK2MAPTRAB9ANPC1
SCHEMBL21884673 0.90 THRB (0.63) THRBPDK2MAPTRAB9ANPC1
SCHEMBL40434 0.90 THRB (0.63) THRBPDK2MAPTRAB9ANPC1
SCHEMBL22648010 0.89 THRB (0.48) THRBPDK2MAPTL3MBTL1RAB9A
SCHEMBL15085061 0.88 THRB (0.64) THRBPDK2MAPTRAB9ANPC1
SCHEMBL21025719 0.87 THRB (0.59) THRBPDK2MAPTRAB9ANPC1
SCHEMBL21025584 0.87 THRB (0.59) THRBPDK2MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718580-B2 Fluorene derivatized monomers and polymers for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-08-08 US disclosed
EP-3966195-B1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECH LLC (US) 2023-07-05 EP disclosed
WO-2020227264-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2020-11-12 WO disclosed
US-20200354311-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-11-12 US disclosed
US-7579066-B2 Ethylenically unsaturated group-containing isocyanate compound and process for producing the same, and reactive monomer, reactive (meth) acrylate polymer and its use SHOWA DENKO K.K. (JP) 2009-08-25 US disclosed
US-20080132597-A1 Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use RESONAC CORPORATION (JP) 2008-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354311-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS RHOA, PARG, LSG1 THRB 4265/4885PDK2 4171/4885MAPT 2962/4885
US-11718580-B2 Fluorene derivatized monomers and polymers for volume Bragg gratings RHOA, PARG, LSG1 THRB 4265/4885PDK2 4171/4885MAPT 2962/4885
US-20080132597-A1 Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use ACAD9, ELOVL6, ELOVL5 THRB 4474/4885PDK2 597/4885MAPT 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.