Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | POLG | P54098 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860484 | 0.87 | FGFR1 (0.50) | FGFR1SLC22A6 | |
| SCHEMBL5720716 | 0.85 | FGFR1 (0.44) | FGFR1SLC22A6POLGPOLB | |
| SCHEMBL5720714 | 0.77 | FGFR1 (0.39) | FGFR1SLC22A6POLGPOLB | |
| SCHEMBL13714879 | 0.76 | POLB (0.61) | POLGPOLBPOLA1 | |
| SCHEMBL13714833 | 0.75 | ENPP1 (0.49) | FGFR1SLC22A6POLGPOLBPOLA1 | |
| SCHEMBL6314090 | 0.74 | FGFR1 (0.43) | FGFR1SLC22A6POLGPOLBPOLA1 | |
| SCHEMBL15531740 | 0.73 | POLB (0.56) | FGFR1SLC22A6POLGPOLBPOLA1 | |
| Cidofovir Diposphate SCHEMBL29390031 | 0.71 | FGFR1 (0.74) | FGFR1SLC22A6POLGPOLBPOLA1 | |
| SCHEMBL3852267 | 0.70 | FGFR1 (0.32) | FGFR1SLC22A6 | |
| SCHEMBL3859402 | 0.67 | FGFR1 (0.41) | FGFR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579332-B2 | Nucleobase phosphonate analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579332-B2 | Nucleobase phosphonate analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2009-08-25 | — | — | US | disclosed |