Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.44 |
| ▸ | AHCY | P23526 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.39 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852148 | 0.88 | FGFR1 (0.54) | ENPP1ENPP3AHCYFGFR1SLC22A6 | |
| SCHEMBL13714845 | 0.88 | FGFR1 (0.54) | ENPP1ENPP3AHCYFGFR1SLC22A6 | |
| SCHEMBL13714886 | 0.83 | AHCY (0.44) | AHCYFGFR1SLC22A6POLA1POLG | |
| SCHEMBL13714879 | 0.82 | POLB (0.61) | POLBPOLA1POLGCYP3A4 | |
| SCHEMBL3852153 | 0.79 | AHCY (0.48) | ENPP1ENPP3AHCYCYP3A4 | |
| SCHEMBL3852157 | 0.79 | AHCY (0.46) | ENPP1ENPP3AHCYFGFR1SLC22A6 | |
| SCHEMBL6004041 | 0.76 | AHCY (0.44) | ENPP1ENPP3AHCYCYP3A4 | |
| SCHEMBL3861066 | 0.76 | FDPS (0.46) | ENPP1ENPP3AHCYFGFR1SLC22A6 | |
| SCHEMBL3853182 | 0.75 | HPRT1 (0.44) | ENPP1AHCYFGFR1SLC22A6CYP3A4 | |
| SCHEMBL13714781 | 0.75 | HPRT1 (0.44) | ENPP1AHCYFGFR1SLC22A6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579332-B2 | Nucleobase phosphonate analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579332-B2 | Nucleobase phosphonate analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2009-08-25 | — | — | US | disclosed |