SCHEMBL13714949

SCHEMBL13714949

CC(=O)c1ccc(CS(=O)(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
LMNA P02545 3/20 0.52
HPGD P15428 4/20 0.51
HSD17B10 Q99714 1/20 0.47
CYP19A1 P11511 1/20 0.46
STS P08842 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 2/20 0.43
RAB9A P51151 1/20 0.43
MAOB P27338 5/20 0.43
PYCR1 P32322 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAOA P21397 2/20 0.42
HSD17B1 P14061 1/20 0.42
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27556694 0.85 KMT2A (0.61) KMT2ALMNAHPGDHSD17B10CYP19A1
SCHEMBL1482125 0.83 KMT2A (0.59) KMT2ALMNAHPGDHSD17B10CYP19A1
SCHEMBL8474031 0.82 CA2 (0.41) KMT2AHSD17B10MAPTSMN1; SMN2
SCHEMBL11128268 0.82 KMT2A (0.38) KMT2ALMNAHPGDHSD17B10CYP19A1
SCHEMBL6171743 0.82 KMT2A (0.57) KMT2ALMNAHPGDHSD17B10STS
SCHEMBL13923500 0.82 KMT2A (0.57) KMT2ALMNAHPGDHSD17B10CYP19A1
SCHEMBL1060743 0.81 TSHR (0.56) KMT2AHSD17B10L3MBTL1MAPTSMN1; SMN2
Sulfuric Acid SCHEMBL28405744 0.79 KMT2A (0.59) KMT2ALMNAHPGDHSD17B10CYP19A1
SCHEMBL29108711 0.79 TSHR (0.55) KMT2AHSD17B10L3MBTL1MAPTSMN1; SMN2
SCHEMBL27414954 0.79 ALDH1A1 (0.39) KMT2AHPGDHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110117237-B Preparation method of aromatic nitrile or alkenyl nitrile compound 中国科学院上海有机化学研究所 2024-02-02 CN disclosed
US-7572459-B2 Prevention infections in humans, animals STARPHARMA PTY LTD. (AU) 2009-08-11 US disclosed