Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 6/20 | 1.00 |
| ▸ | DYRK2 | Q92630 | 3/20 | 1.00 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.73 |
| ▸ | RAF1 | P04049 | 2/20 | 0.64 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | AKT1 | P31749 | 2/20 | 0.64 |
| ▸ | AKT2 | P31751 | 2/20 | 0.64 |
| ▸ | KDR | P35968 | 2/20 | 0.64 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.64 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.64 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.64 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.64 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.64 |
| ▸ | EP300 | Q09472 | 2/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | PRDX1 | Q06830 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719651 | 1.00 | IKBKB (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL29928839 | 1.00 | IKBKB (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL29929418 | 0.78 | DYRK2 (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL29363457 | 0.78 | IKBKB (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL29786707 | 0.78 | IKBKB (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL13036873 | 0.78 | DYRK2 (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL7122621 | 0.78 | DYRK2 (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL7122623 | 0.78 | DYRK2 (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL17691411 | 0.78 | IKBKB (0.64) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 | |
| SCHEMBL30593591 | 0.78 | IKBKB (1.00) | IKBKBDYRK2HSD11B1RAF1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359196-B2 | Antiproliferative compositions comprising curcumin analogs and methods of producing and using same | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2016-06-07 | — | — | US | disclosed |
| US-20120288555-A1 | ANTIPROLIFERATIVE COMPOSITIONS COMPRISING CURCUMIN ANALOGS AND METHODS OF PRODUCING AND USING SAME | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288555-A1 | ANTIPROLIFERATIVE COMPOSITIONS COMPRISING CURCUMIN ANALOGS AND METHODS OF PRODUCING AND USING SAME | MCL1, LITAF, CTSA | IKBKB 3061/4885DYRK2 4648/4885HSD11B1 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.