SCHEMBL13720116

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14727	1.00	PTGES (0.39)	PTGESMAPTLPAR1FFAR1CYP3A4
	SCHEMBL14736	0.91	MAPT (0.36)	PTGESMAPTLPAR1CYP3A4CYP1A2
	SCHEMBL13830939	0.87	IP6K1 (0.43)	MAPTLPAR1CYP3A4CYP1A2CYP2D6
	SCHEMBL13720242	0.86	LPAR1 (0.51)	MAPTLPAR1CYP3A4CYP1A2CYP2D6
	SCHEMBL14570	0.86	FFAR1 (0.47)	MAPTLPAR1FFAR1CYP3A4CYP1A2
	SCHEMBL18575635	0.84	CYP3A4 (0.38)	MAPTLPAR1CYP3A4CYP1A2CYP2D6
	SCHEMBL18575636	0.84	PPARD (0.40)	MAPTLPAR1FFAR1CYP3A4CYP1A2
	SCHEMBL13831064	0.83	USP2 (0.44)	MAPTLPAR1CYP3A4CYP1A2CYP2D6
	SCHEMBL6986	0.83	LPAR1 (0.51)	MAPTLPAR1CYP3A4CYP1A2CYP2D6
	SCHEMBL1732	0.82	LMNA (0.40)	MAPTLPAR1CYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.