Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721999 | 0.91 | GSK3B (0.58) | GSK3BCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL13722200 | 0.90 | GSK3B (0.59) | GSK3BCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL13722076 | 0.88 | GSK3B (0.56) | GSK3BCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL13910418 | 0.88 | GSK3B (0.77) | GSK3BCYP2D6ALDH1A1MAPTTSHR | |
| SCHEMBL4029898 | 0.88 | GSK3B (0.77) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4031690 | 0.87 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13721615 | 0.87 | GSK3B (0.54) | GSK3BCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL4026310 | 0.87 | GSK3B (0.77) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13722178 | 0.87 | GSK3B (0.61) | GSK3B | |
| SCHEMBL4024539 | 0.87 | GSK3B (0.77) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |