Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13722008 | 0.91 | GSK3B (0.54) | GSK3BCYP2D6 | |
| SCHEMBL14063487 | 0.90 | GSK3B (0.69) | GSK3BNR1H4 | |
| SCHEMBL13721715 | 0.88 | GSK3B (0.59) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13721615 | 0.88 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13721999 | 0.86 | GSK3B (0.58) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13721621 | 0.84 | GSK3B (0.53) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13722013 | 0.84 | GSK3B (0.78) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4029898 | 0.83 | GSK3B (0.77) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4031690 | 0.83 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4024539 | 0.82 | GSK3B (0.77) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |