Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13722113 | 0.93 | NT5E (0.34) | NT5EP2RY6P2RY2P2RY14DUT | |
| SCHEMBL13721986 | 0.92 | NT5E (0.39) | NT5EP2RY6P2RY2P2RY14DUT | |
| SCHEMBL13722156 | 0.81 | NT5E (0.39) | NT5EP2RY6P2RY2P2RY14KMT2A | |
| SCHEMBL13722164 | 0.81 | NT5E (0.39) | NT5EP2RY6P2RY2P2RY14DUT | |
| SCHEMBL4078631 | 0.77 | NT5E (0.36) | NT5EP2RY6P2RY14DUT | |
| SCHEMBL13721996 | 0.76 | ABL1 (0.41) | NT5EP2RY6P2RY2P2RY14 | |
| SCHEMBL13722327 | 0.75 | P2RY14 (0.33) | NT5EP2RY6P2RY2P2RY14KMT2A | |
| SCHEMBL13722314 | 0.73 | P2RY6 (0.40) | NT5EP2RY6P2RY2P2RY14DUT | |
| SCHEMBL13722472 | 0.71 | DUT (0.37) | NT5EP2RY6P2RY2P2RY14DUT | |
| SCHEMBL4078632 | 0.71 | NT5E (0.40) | NT5EP2RY6P2RY2P2RY14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |